You can create a 2x3 grid using Auto Layout frames, grouping the buttons by Row or Column. Very similar to how a Table/Data Grid works.

This way it’s easier to control the buttons position and spacing without needing to edit them one by one.

To create an Auto Layout frame, place the buttons where you want, then select all of them together and press Shift+A, or right-click the selection and choose Add Auto-Layout

See an example of buttons grouped by Row inside a grid below:

See an example of buttons grouped by Column inside a grid below:

Don’t forget to set the Auto Layout direction and spacing!