To my knowledge, no, and that would be a great feature.
Some exceptions:
- Equal parts layout (50-50, 25-25-25-25, and so on): using “Fill container”, you can have content grow to use space in equal parts (if you have two elements, they’ll each take half of the container, 3 will take a third, etc)
- Column layout: without using auto layout, you can use the columns and constraints to have content resize according to columns. But as a “normal frame”, this is limited to one dimension. This was discussed here.
There might be some other ways to achieve this but not that I’m currently aware of.